We're on a mission to eradicate neurodegenerative diseases.

Our Team

Our team is pound for pound one of the best in the world for developing drugs targeting protein aggregation disorders. Featuring multiple senior leaders from renowned organizations including Janssen, Elan, Merck, Prothena, and Jazz Pharmaceuticals, all of whom bring extensive preclinical and clinical experience in anti-AB monoclonal antibodies. Our high transparency culture provides everyone with an opportunity to contribute and challenge ideas, even outside their traditional areas of expertise. This collaborative environment fosters innovation and ensures that our drug development processes benefit from diverse experiences.


Founding Team & Leadership

Frederic Godderis

Co - Founder & Chief Executive Officer

Trebor Lawton

Co - Founder & Chief Technology Officer

Eric Yuen MD

Chief Medical Officer

Enchi Liu

Chief Development Officer

Saira Ramasastry

Corporate Strategy

Guriq Basi PhD

Preclinical Development

Noah Ullman

Co - Founder

Dr. Robert Lawton PhD.

Founding Scientist

Scientific Advisory Board

Guriq Basi PhD

Current: SAB Chair & Preclinical Development @ Abyssinia. Former: CSO/ CTO @ Sarepta & Elan

Dennis Selkoe MD

Current: Co-director, Ann Romney Center for Neurologic Diseases

Vincent and Stella Coates Professor of Neurologic Diseases, Harvard Medical School

Coming Soon

Consultants & Advisors

Erica Pascal PhD

Intellectual Property

Raj Dua PhD

CMC

Paul Treacy PhD

CMC

Brian Rogers PhD

Toxicology

Steve Sazinksy PhD

Protein Engineering

Michael Papile

Corporate Finance

Mark Matijevic

Translational Science & Biomarkers

Peter Hoehn

Biomarkers & Diagnostics

Ira Wallis

Regulatory Affairs

Sam Griffin

R&D Intern

Our Science

Why Oligomers?

Treat

Soluble oligomers of amyloid-beta (Aβ)  are believed to be the most neurotoxic forms of Aβ. Unlike insoluble plaques, these soluble oligomers can disrupt synaptic function, impair neuronal communication, and lead to cognitive deficits even at low concentrations. They are thought to play a central role in the early stages of Alzheimer’s, contributing to synaptic loss and neurodegeneration as well as driving downstream pathologies like tau dysregulation.

Prevent

By stimulating the immune system to recognize and neutralize toxic oligomers before they aggregate into plaques, a vaccine could potentially prevent the initial synaptic dysfunction and neuronal damage that leads to cognitive decline. This preemptive action would address the disease at an early stage, ideally halting its progression before significant brain damage occurs. Additionally, targeting oligomers specifically avoids the risks associated with removing amyloid plaques, which may sometimes lead to adverse effects. 

Diagnose

Soluble amyloid-beta (Aβ) is a crucial biomarker for Alzheimer’s disease due to its early involvement in disease pathogenesis. Monitoring soluble Aβ levels, particularly oligomers, provides insights into disease onset and progression before symptoms appear. Detecting Aβ in plasma offers minimally invasive, repeatable measurements for large-scale screening and longitudinal studies, while cerebrospinal fluid (CSF) analysis, though more invasive, provides a closer reflection of central nervous system changes with higher sensitivity and specificity. 

Contact Us

Phone

Email

855 Boylston St. #1000
Boston MA 02116